http://medspecial.ru Новое в теме Клиническая фармакология форума на сайте medspecial.ru [medspecial.ru] ru http://backend.userland.com/rss2 Sat, 16 May 2026 07:38:20 +0300 Клиническая фармакология в форуме Иностранные ресурсы.

H. Winter Griffith, "Complete Guide to Prescription & Nonprescription Drugs 2014"
ISBN: 1594631972 | 2013 |

The 2014 edition of the most accessible, comprehensive and affordable “outstanding reference source.”

The classic guide to all major prescription and nonprescription drugs, featuring revised, up to date FDA information and an A-Z list of illnesses for easy reference. Includes coverage of dosage and length of time before drug takes effect; side effects, special precautions; interactions with other food and drugs; standards for use by different age groups, and more.
07.12.13 21:50, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message14600/ http://medspecial.ru/forum/messages/forum77/topic337/message14600/ Sat, 07 Dec 2013 21:50:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Brenda Predham, Susan Buchholz, "Henke's Med-Math"
English | ISBN: 0781799864 | 2009 |

Now fully adapted to reflect Canadian drug information, measurement, legislation, and standards, Henke's Med Math, First Canadian Edition is an excellent choice for giving students an in-depth understanding of dosage calculation and principles of drug administration. It presents step-by-step approaches to solving problems and includes dosage problems that simulate actual clinical experience. Each chapter includes numerous examples, self-tests, and proficiency tests. Multiple dosage calculation methodologies—formula, ratio, proportion, and dimensional analysis—are taught, allowing students to adopt their preferred method. In addition, calculations are included for intravenous pediatric, PCA, and critical care medications.
03.12.13 7:57, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message14504/ http://medspecial.ru/forum/messages/forum77/topic337/message14504/ Tue, 03 Dec 2013 07:57:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Brian L. Strom, "Textbook of Pharmacoepidemiology, 2nd Edition"
English | ISBN: 1118344863 | 2013 | 480 pages

Textbook of Pharmacoepidemiology , Second Edition, provides an introduction to pharmacoepidemiology and the methodologies, data sources and applications used in clinical practice, the pharmaceutical industry and regulatory agencies. This second edition includes new and updated learning features, case examples and key points, as well as information on the new pharmacoepidemiology databases and how to use them.
08.08.13 21:15, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message12501/ http://medspecial.ru/forum/messages/forum77/topic337/message12501/ Thu, 08 Aug 2013 21:15:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Kevin Woodward, "Toxicological Effects of Veterinary Medicinal Products in Humans: Volume 1"
2013 | ISBN-10: 1849734178 | 500 pages

Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans. The chapters focus on occupational safety and consumer issues and examine the circumstances under which exposure is likely to occur. To be in context, it reviews this against the background of adverse health effects from other sources in the veterinary and farming professions. The book examines adverse drug effects reported to regulatory agencies (mainly the FDA’s Center for Veterinary Medicine) and then considers a series of individual drugs, including antibiotics, anaesthetics and organophosphorus compounds. The chapters also discuss the fundamental aspects of regulatory issues relating to safety assessment, and examine the manner in which user safety is assessed prior to authorisation/approval and what measures can be taken after authorisation/approval in the light of findings from pharmacovigilance activities. There is growing concern over the issue of antimicrobial resistance and the contribution made by veterinary medicinal products. This too is addressed along with the significance to human health and measures that can be taken to mitigate the effects (if any) of the use of antibiotics in animals e.g. prudent use measures. The book will be an essential resource for medical practitioners in hospitals and general practice, pharmaceutical industry scientists, analysts, regulators and risk managers.
03.08.13 21:13, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message12335/ http://medspecial.ru/forum/messages/forum77/topic337/message12335/ Sat, 03 Aug 2013 21:13:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Xianhai Huang, "Case Studies in Modern Drug Discovery and Development"
ISBN: 0470601817 | 2012 | 473 pages
03.08.13 13:52, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message12256/ http://medspecial.ru/forum/messages/forum77/topic337/message12256/ Sat, 03 Aug 2013 13:52:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Drug Repositioning: Bringing New Life to Shelved Assets and Existing Drugs by Michael J. Barratt and Donald E. Frail
English | 2012 | ISBN: 0470878274 | 498 pages

The how's and why's of successful drug repositioning
Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers.

Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy.

Drug Repositioning is divided into three parts:

• Part 1, Drug Repositioning: Business Case, Strategies, and Operational Considerations, examines the medical and commercial drivers underpinning the quest to reposition existing drugs, guiding readers through the key strategic, technical, operational, and regulatory decisions needed for successful drug repositioning programs.
• Part 2, Application of Technology Platforms to Uncover New Indications and Repurpose Existing Drugs, sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents.
• Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry, explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return.
The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits.
With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development.
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Drug Discovery: Practices, Processes, and Perspectives by Jie Jack Li and E. J. Corey
English | 2013 | ISBN: 0470942355 | 570 pages

Sets forth the history, state of the science, and future directions of drug discovery
Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work.

Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design.

Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contributions are based on a thorough review of the current literature as well as the authors' firsthand laboratory experience in drug discovery. The book begins with the history of drug discovery, describing groundbreaking moments in the field. Next, it covers such topics as:

• Target identification and validation
• Drug metabolism and pharmacokinetics
• Central nervous system drugs
• In vitro and in vivo assays
• Cardiovascular drugs
• Cancer drugs
Each chapter features a case study, helping readers understand how science is put into practice throughout all phases of drug discovery. References at the end of each chapter serve as a gateway to groundbreaking original research studies and reviews in the field.
Drug Discovery is ideal for newcomers to medicinal chemistry and drug discovery, providing a comprehensive overview of the field. Veterans in the field will also benefit from the perspectives of leading international experts in all aspects of drug discovery.
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John P. Griffin, "The Textbook of Pharmaceutical Medicine, 7 edition"
English | ISBN: 0470659874 | 2013 | 854 pages

The Textbook of Pharmaceutical Medicine is the standard reference for everyone working and learning in pharmaceutical medicine. It is a comprehensive resource covering the processes and practices by which medicines are developed, tested and approved, and the recognised text for the Diploma in Pharmaceutical Medicine from the Faculty of Pharmaceutical Medicine.

This fully revised Seventh Edition, which includes two new Editors, encompasses current developments within pharmaceutical medicine with new chapters on biological therapeutics, pharmacovigilance, vaccines, drugs for cancer, drug development in paediatrics and neonatalogy, the clinical trials directive, life cycle management of medicines, counterfeit medicines and medical marketing. Also included for easy reference, and referred to throughout the text, are the Declaration of Helsinki, Guidelines and Documentation for Implementation of Clinical Trials, relevant European Directives and the Syllabus for Pharmaceutical Medicine.

Written by an international team of leading academics, medical directors and lawyers, The Textbook of Pharmaceutical Medicine, Seventh Edition meets the needs of both those working in pharmaceutical medicine and preparing for the Diploma in Pharmaceutical Medicine.

The text breaks down into three core sections:

Part I: Research and Development
Part II: Regulation
Part III: Healthcare marketplace
03.08.13 13:49, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message12253/ http://medspecial.ru/forum/messages/forum77/topic337/message12253/ Sat, 03 Aug 2013 13:49:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

"Using Old Solutions to New Problems: Natural Drug Discovery in the 21st Century" ed. by Marianna Kulka
InTeOpP | 2013 | ISBN: 9535111580 9789535111580 | 423 pages

This book is a collection of an expert team of agronomists, chemists, biologists and policy makers who discuss some of the processes involved in developing a naturally-sourced bioactive compound into a drug therapy. These experts define a natural compound and elucidate the processes required to find, extract and define a naturally-derived bioactive molecule, they describe the necessity for understanding the fundamental mechanisms of disease before applying bioactive molecules in bioassay-guided drug discovery platforms

The medicinal use of plants, animals and microorganisms has been a part of human evolution and likely began before recorded history. Is it possible that this knowledge can be used to create powerful new drugs and solve some of the human health problems facing us today?

Contents
Preface
Section 1 Agronomy and Molecular Characterization
1 Discovery, Development, and Regulation of Natural Products
2 Genetic, Agronomy, and Metabolomics of Prince Edwards Island Wild Rose Collection and Promise for Cultivar Development
3 Magnetic Resonance Technologies: Molecules to Medicine
Section 2 Bioactive Proteins from Natural Sources
4 Marine Natural Products for Protein Misfblding Modulation
5 Marine Flatfish-Derived Bioactive Peptides: From the Ocean to the Bedside
Section 3 Bioactive Ingredients in Nutrition
6 Anticancer Properties of Phytochemicals Present in Medicinal Plants of North America
7 A New Perspective on the Development of Cholesterol-Lowering Products
8 A Glance at the Complexity of Nutrition and the Prostate: Considering Molecular Targets to Unravel the Most Recent Controversy Between Omega-3 Fatty Acids and Their Impact on Prostate Cancer Risk
Section 4 Bioactive Compounds in Health and Disease
9 Mechanisms and Treatment of Photoaging and Photodamage
10 Asthma in the 21st Century — Unexpected Applications of Ancient Treatments
11 Plant Based Natural Products and Breast Cancer: Considering Multi-Faceted Disease Aspects, Past Successes, and Promising Future Interventions
05.07.13 11:59, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message11673/ http://medspecial.ru/forum/messages/forum77/topic337/message11673/ Fri, 05 Jul 2013 11:59:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Ajay K Banga, "Transdermal and Intradermal Delivery of Therapeutic Agents: Application of Physical Technologies"
Publisher: C--C Press | ISBN: 1439805091 | 2011 | 300 pages


Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment. Advancements in science combined with the need for diverse drug delivery modalities have introduced a variety of transdermal and intradermal products for existing drugs at a fraction of the cost of new drug development. Commercialization of transdermal drug delivery requires technology from many disciplines beyond pharmaceutical sciences, such as polymer chemistry, adhesion sciences, mass transport, web film coating, printing, and medical technology.

A comprehensive discussion of these technologies and practices, Transdermal and Intradermal Delivery of Therapeutic Agents: Application of Physical Technologies covers:

Commercial development of devices and products based on transdermal physical enhancement technologies
Selecting optimal enhancement technology for a specific drug molecule using case studies
Physicochemical properties and practical commercial considerations related to cost, unmet clinical needs, marketing, or intellectual property protection
Technologies such as microneedles, iontophoresis, electroporation, and sonophoresis, with examples for delivery of small molecules, cosmeceuticals, proteins, and vaccines
Practical information on experimental procedures and challenges related to skin irritation and safety issues

Up-to-date and accessible to researchers and industry experts, this book provides a comprehensive discussion of the physical approaches and practical considerations for the laboratory and marketplace.
05.07.13 11:51, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message11668/ http://medspecial.ru/forum/messages/forum77/topic337/message11668/ Fri, 05 Jul 2013 11:51:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.
Journal of Pharmaceutical Policy and Practice

Abbreviation: J Pharm Policy and Pract

ISSN: 2052-3211

URL: http://www.joppp.org

Journal of Pharmaceutical Policy and Practice  (formerly known as Southern Med Review ) is an open access, peer-reviewed journal. It provides a
platform for researchers to disseminate empirical research findings, with the aim that people everywhere have access to the medicines they need and use them rationally.

Journal of Pharmaceutical Policy and Practice  encompasses all aspects of pharmacy whether clinical, social, administrative or economic, and provides a platform to researchers, academics and practitioners from around the world to share new evidence, concerns and perspectives.
16.06.13 14:42, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message10865/ http://medspecial.ru/forum/messages/forum77/topic337/message10865/ Sun, 16 Jun 2013 14:42:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Inhaler devices: Fundamentals, design and drug delivery by Polina Prokopovich
English | 2013 | ISBN: 0857094963 | ISBN-13: 9780857094964 | 192 pages


Given their direct impact on the health and quality of life for millions of people, inhalers represent a major turning point in the history of modern medicine. The editor and contributors provide an introduction to the fundamentals of inhaler technology, with a comprehensive discussion of the history of inhalers as well as a discussion on current research and development.
Chapters look at the fundamentals of the in vitro environment and design of inhaler devices and review a wide variety of nanomaterials for drug delivery through inhalers.
25.05.13 10:22, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message10189/ http://medspecial.ru/forum/messages/forum77/topic337/message10189/ Sat, 25 May 2013 10:22:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Virginia E. Wotring - Space Pharmacology
Published: 2012-03-18 | ISBN: 1461433959 | 120 pages

“Space Pharmacology” is a review of the current knowledge regarding the use of pharmaceuticals during spaceflights. It is a comprehensive review of the literature, addressing each area of pharmacokinetics and each major physiological system in turn. Every section begins with a topic overview, and is followed by a discussion of published data from spaceflight, and from ground experiments meant to model the spaceflight situation. Includes a discussion looking forward to the new medical challenges we are likely to face on longer duration exploration missions. This book is a snapshot of our current knowledge that also highlights areas of unknown.
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Timothy G. K. Mant, Lionel D Lewis, James M Ritter, Albert Ferro - Clinical Pharmacology and Therapeutics: Questions for Self Assessment (3rd edition)
Published: 2008-04-25 | ISBN: 0340947438 | 218 pages

So you think you've got a handle on therapeutic management? How drugs work and interact with each other, how the body handles them and how drug treatments are assessed?
This self-assessment volume allows you to learn, revise and test yourself on all aspects of clinical pharmacology and therapeutics. Four different question types are provided to test your knowledge in this important area - multiple choice questions, extended matching questions, 'best of fives' and problem-solving questions. Detailed explanatory answers ensure this book solves your queries as well as providing essential revision for those all-important exams.
Test your knowledge with Clinical Pharmacology and Therapeutics: Questions for Self Assessment and not only develop your exam technique but become a better prescriber.
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Ben Greenstein, Daniel A. Brook - Biological Therapeutics
Published: 2011-02-09 | ISBN: 0853698430 |  138 pages

An introduction to what is arguably the most exciting and fastest-growing branch of pharmaceutical science at the present time: the treatment of disease using biological medicines derived from living plant and animal tissues. All categories of biological therapeutics are covered in this comprehensive overview. Chapter features include: * historical introductions * an overview of the drugs and their mechanisms of action and uses * examples of adverse reactions * case studies This book is essential reading for medical and pharmacy students, as well as practitioners and prescribers aiming to keep up to date with the latest developments in biological medicines.
18.05.13 12:56, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message9887/ http://medspecial.ru/forum/messages/forum77/topic337/message9887/ Sat, 18 May 2013 12:56:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Martin Stephens - Hospital Pharmacy (2nd edition)
Published: 2011-04-11 | ISBN: 0853699003 | 313 pages

Hospital Pharmacy outlines the changes in pharmacy practice within the hospital setting and discusses the vast range of services that are provided. Each chapter is devoted to an area of pharmacy practice and discusses its history, current practice and future developments. This new edition has been completely revised and updated and includes new chapters on: pharmacy in the acute independent sector; controlled drugs in hospital pharmacy; pharmacist prescribing; mental health; and consultant pharmacists. This book is essential reading for pharmacy undergraduates, pre-registration graduates and newly qualified pharmacists as well as a key reference text for all hospital pharmacists departments. With its broad all-encompassing coverage it will also be of interest to other healthcare professionals.
18.05.13 12:54, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message9886/ http://medspecial.ru/forum/messages/forum77/topic337/message9886/ Sat, 18 May 2013 12:54:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

An introduction to pharmaceutical sciences: Production, chemistry, techniques and technology By Jiben Roy
2011 | 446 Pages | ISBN: 1907568522 |


The key theme of this textbook is pharmaceuticals: what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry.

Dr. Jiben Roy explains how a particular drug is discovered and then converted from lab scale to manufacturing scale to the market. He explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After reading the book, the student will be able to understand the career prospects in the pharmaceutical industry, the need for interdisciplinary teamwork in science, the techniques and technology involved in making pharmaceuticals. Chapters discuss in detail a few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin and the longest serving drugs such as aspirin and paracetamol. It also covers important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for the pharmaceutical industry.
18.05.13 12:53, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message9885/ http://medspecial.ru/forum/messages/forum77/topic337/message9885/ Sat, 18 May 2013 12:53:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Markus Müller - Clinical Pharmacology: Current Topics and Case Studies
Published: 2010-11-04 | ISBN: 3709101433 | 454 pages

Today we witness an eventful time in which the powerful new forces of genomics, information technology and economics are rapidly changing the science and art of medicine. This will require more specialization than ever before. However, there is also an increasing demand for an integrated approach, which is provided by the discipline of Clinical Pharmacology (CP). CP pursues a scientific goal by studying drug action in patients and volunteers, a clinical goal by administering appropriate drug therapy and a regulatory goal by assessing the risk/benefit ratio of drug candidates in drug development and reimbursement. This introduction to current topics of CP covers traditional topics of clinical drug research and trial methodology but also provides insight in current topics like genomics, imaging technology and issues in drug reimbursement. A number of concrete case studies in clinical drug research and development help to give a better understanding of the general principles of CP.
18.05.13 10:58, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message9852/ http://medspecial.ru/forum/messages/forum77/topic337/message9852/ Sat, 18 May 2013 10:58:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Jeremy C. Wright, Diane J. Burgess
"Long Acting Injections and Implants"
English | ISBN: 146140553X | 2011 | 572 pages

Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability. An intriguing variety of technologies have been developed to provide long acting injections and implants. Many considerations need to go into the design of these systems in order to translate a concept from the lab bench to actual therapy for a patient. This book surveys and summarizes the field. Topics covered in Long Acting Injections and Implants include the historical development of the field, drugs, diseases and clinical applications for long acting injections and implants, anatomy and physiology for these systems, specific injectable technologies (including lipophilic solutions, aqueous suspensions, microspheres, liposomes, in situ forming depots and self-assembling lipid formulations), specific implantable technologies (including osmotic implants, drug eluting stents and microfabricated systems), peptide, protein and vaccine delivery, sterilization, drug release testing and regulatory aspects of long acting injections and implants. This volume provides essential information for experienced development professionals but was also written to be useful for scientists just beginning work in the field and for others who need an understanding of long acting injections and implants. This book will also be ideal as a graduate textbook.
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Dosage Calculations: A Ratio-Proportion Approach

Gloria D. Pickar
Publisher: Delmar Cengage Learning; 2 edition (August 22, 2006) | ISBN: 1418015636 | Pages: 565

Master dosage calculations with the ratio-proportion version of the best-selling book from Gloria D. Pickar! Dosage Calculations: A Ratio-Proportion Approach 2e builds upon core strengths that made Dosage Calculations a market leader. This trusted book includes a comprehensive math review, full-color drug labels, and critical thinking assessments. Basic and advanced calculations are thoroughly covered, including intravenous and those specific to the pediatric patient.
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Mr Ro ger McF adden

"Introducing Pharmacology: For Nursing and Healthcare"
English | 2009 | ISBN: 0273718630 | 320 pages

Pharmacology concerns all practitioners of medicine and is essentially the science of drugs. It calls for the use of techniques from many other fields, such as biochemistry, statistics, and epidemiology, and can therefore prove to be a challenging subject.
Introducing Pharmacology has been specially written for nursing and healthcare professionals, both trainees and qualified practitioners. The book provides an easy to understand introduction to Pharmacology that nursing and healthcare professionals will find relevant from the beginning of clinical training at the hospital, and afterwards in medical practice.
28.10.12 14:11, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message4289/ http://medspecial.ru/forum/messages/forum77/topic337/message4289/ Sun, 28 Oct 2012 14:11:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.
NIH launches free database of drugs associated with liver injury
www.livertox.nih.gov

http://www.nih.gov/news/health/oct2012/niddk-12.htm
A free source of evidence-based information for health care professionals and for researchers studying liver injury associated with prescription and over-the-counter drugs, herbals, and dietary supplements is now available from the National Institutes of Health. Researchers and health care professionals can use the LiverTox database to identify basic and clinical research questions to be answered and to chart optimal ways to diagnose and control drug-induced liver injury.
Drug-induced liver injury is the leading cause of acute liver failure in the United States, accounting for at least half of cases. It occurs at all ages, in men and women, and in all races and ethnic groups. Drug-induced liver disease is more likely to occur among older adults because they tend to take more medications than younger people. Some drugs directly damage the liver, while others cause damage indirectly or by an allergic reaction. The most important element to managing drug-induced liver injury is to identify the drug that’s causing the problem and appropriate steps to eliminate or reduce damage to the liver.
"Because drug-induced liver disease is not a single, common disease, it is very difficult to diagnose, with each drug causing a somewhat different pattern of liver damage," said Jay H. Hoofnagle, M.D., the major creator of LiverTox and director of the Liver Disease Research Branch at NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). "Doctors have to rule out all other causes of liver disease before saying that a patient has drug-induced injury liver."
LiverTox has a searchable database of about 700 medications available in the United States by prescription or over the counter. Over the next few years, another 300 drugs will be added. The database offers these features:

• An overview of drug-induced liver injury, including diagnostic criteria, the role of liver biopsy, descriptions of different clinical patterns and standard definitions.
  
• A detailed report of each drug, including background, case study, product package insert, chemical makeup and structure, dose recommendations and references with links.
  
• An interactive section, allowing users to report cases of drug-induced liver injury to the LiverTox website. Reports will be automatically forwarded to the Food and Drug Administration's (FDA) MedWatch program. MedWatch allows the public and health care professionals to report adverse events, product defects, or product use errors. The FDA uses the information to monitor product safety.
  

"LiverTox is the result of a significant scientific collaboration between the national and international clinical and research communities, the NIDDK and the National Library of Medicine (NLM)," said Steven Phillips, M.D., co-sponsor of LiverTox and director of NLM’s Division of Specialized Information Services. "LiverTox demonstrates the importance of using informatics to provide easy access to evidenced-based information to clinicians and researchers that will improve the health and well-being of all and help prevent unnecessary morbidity and mortality, worldwide. I hope the dynamic LiverTox model can be used to create a new suite of databases that can identify drug-induced injury to other organs such as the heart, kidney, and lung. The National Library of Medicine is honored to be part of this significant scientific endeavor."
The developers of LiverTox worked with outside experts in drug-induced liver disease as well as specialists in arthritis, cancer, diabetes, infectious diseases, and other conditions. The content of each section of the database has been reviewed by an outside expert. The finished website has also been reviewed by FDA and pharmaceutical industry experts on liver-related complications.
"By integrating data that tends to be scattered across the published literature into a single, readily accessible place, we hope to bring greater focus and interest to the study of drug-induced liver injury, and to guide doctors involved with patient care and ultimately, reduce liver injury and improve the health of people," said Hoofnagle.
The database will be updated regularly with information about drug-induced liver injury as well as new drugs and new concepts. LiverTox welcomes input and comments from users through the website, at www.livertox.nih.gov .
The NIDDK, part of the NIH, conducts and supports basic and clinical research and research training on some of the most common, severe and disabling conditions affecting Americans. The Institute's research interests include: diabetes and other endocrine and metabolic diseases; digestive diseases, nutrition, and obesity; and kidney, urologic and hematologic diseases. For more information, visit www.niddk.nih.gov.
The National Library of Medicine (NLM) is the world's largest library of the health sciences and collects, organizes and makes available biomedical science information to scientists, health professionals and the public. For more information, visit http://www.nlm.nih.gov.
20.10.12 14:54, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message4089/ http://medspecial.ru/forum/messages/forum77/topic337/message4089/ Sat, 20 Oct 2012 14:54:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Michael Adams, Leland Norman Holland, Carol Q. Urban
Pharmacology for Nurses: A Pathophysiologic Approach (3rd edition)
Published: 2010-02-09 | ISBN: 0135089816 | 944 pages
06.10.12 17:58, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message3823/ http://medspecial.ru/forum/messages/forum77/topic337/message3823/ Sat, 06 Oct 2012 17:58:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Pharmacology for the Physical Therapist
English | ISBN: 0071460438 | 608 pages | Dat a: 2008

Description: The first pharmacology book for physical therapists written by physical therapists and PhD pharmacologists. Based on the classic Katzung's Basic and Clinical Pharmacology, this ground-breaking book illuminates the ever-expanding role of pharmacology in rehabilitation practice. In it you'll find unmatched insights on the full range of pharmacology topics, from drug receptor pharmacodynamics and general anesthetics, to cancer chemotherapy-all told from the vantage point of the authors' extensive first-hand experience.
05.10.12 18:02, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message3765/ http://medspecial.ru/forum/messages/forum77/topic337/message3765/ Fri, 05 Oct 2012 18:02:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 16 edition

R. R. Berardi, S. P. Ferreri, A. L. Hume, L. A. Kroon, G. D. Newton
English | 2009 | ISBN: 1582121222 | 1050 pages | PDF | 262 Mb

Thoroughly updated and revised, the Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 16th edition, helps students and practitioners develop problem-solving skills needed to assess and triage a pharmacy patient s medical problems. It provides U.S. Food and Drug Administration-approved dosing information and evidence-based research on the efficacy and safety of over-the-counter and herbal medications.
05.10.12 17:57, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message3761/ http://medspecial.ru/forum/messages/forum77/topic337/message3761/ Fri, 05 Oct 2012 17:57:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Poisoning And Drug Overdose, 5th edition (Olson, Poisoning and Drug)
Kent R. Olson
English | 2006 | ISBN: 0071443339 | 736 pages
05.10.12 17:53, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message3759/ http://medspecial.ru/forum/messages/forum77/topic337/message3759/ Fri, 05 Oct 2012 17:53:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

June Olsen, Anthony Giangrasso, Dolores Shrimpton
"Medical Dosage Calculations: A Dimensional Analysis Approach, 10th Edition"
English | ISBN: 013215661X | 2011 | 400 pages

Fully revised for current practices and medication, this MEDICAL DOSAGE CALCULATIONS: A DIMENSIONAL ANALYSIS APPROACH, 10/e remains the field’s most complete, user-friendly and accessible drug calculation text and workbook. Using the dimensional analysis format it pioneered, students begin with simple arithmetic, progressing to the most complex drug calculations. As they develop mathematical skills for accurate dosage calculations, they also gain a thorough professional understanding of safe drug administration. Compared with competitors, our text contains deeper, more realistic problems, incorporating actual dosages and requiring real critical thinking. Coverage includes titrations, IV push, VCC, and other complex calculations. Updates include: revised safety recommendations and insulin coverage; new equipment and labeling photos; and 0.5 mL and needleless syringes. Pedagogical aids include case studies, self-tests, and a website for student resources.
05.07.12 20:56, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message2050/ http://medspecial.ru/forum/messages/forum77/topic337/message2050/ Thu, 05 Jul 2012 20:56:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Handbook of Antimicrobial Therapy

Medical Letter, Mark Abramowicz, M.D. and Gianna Zuccotti
English | 2011 | ISBN: 0981527825 | 242 double pages

The Medical Letter, Inc. is a nonprofit company founded in 1958 by Arthur Kallet, the co-founder of Consumers Union, and Dr. Harold Aaron, with the goal of providing healthcare professionals with objective, independent analyses of both prescription and over-the-counter drugs. In addition to its newsletters, The Medical Letter on Drugs and Therapeutics and Treatment Guidelines from The Medical Letter, the company also publishes handbooks and software on topics such as antimicrobial therapy and adverse drug interactions. It is supported solely by subscription fees and accepts no advertising, grants or donations.
05.07.12 20:46, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message2046/ http://medspecial.ru/forum/messages/forum77/topic337/message2046/ Thu, 05 Jul 2012 20:46:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Clinical Pharmacology Made Ridiculously Simple
Medmaster; 2nd edition | 2003 | ISBN-10: 094078050X | 163 pages

A concise overview of the most important principles in clinical pharmacology, with drug comparisons in clear chart format. Excellent Board review
23.06.12 14:03, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message1784/ http://medspecial.ru/forum/messages/forum77/topic337/message1784/ Sat, 23 Jun 2012 14:03:00 +0300 Иностранные ресурсы Клиническая фармакология в форуме Иностранные ресурсы.

Susan M. Ford, Sally S. Roach
"Roach's Introductory Clinical Pharmacology, 9th Edition"
Lippincott | 2009 | ISBN: 1605476331 | 784 pages

This core text offers LPN/LVN students a clear, concise introduction to pharmacology, focusing on basic principles and the nurse's responsibility in drug administration. Organized by body system, the book examines pharmacologic properties and therapeutic applications of drug classes. Summary Drug Tables present generic and trade drug names, uses, adverse reactions, and usual dosage ranges. This edition has thoroughly updated drug information, a new "Pharmacology in Practice" case study feature, Nursing Alerts, Lifespan Alerts, Chronic Care Alerts, Diversity Alerts, and additional material on the nursing process.
23.06.12 14:02, Жозефа.]]> http://medspecial.ru/forum/messages/forum77/topic337/message1783/ http://medspecial.ru/forum/messages/forum77/topic337/message1783/ Sat, 23 Jun 2012 14:02:00 +0300 Иностранные ресурсы